The choice of risk management strategy should take into account current age, other health issues and age-related cancer risk. Risks and benefits of interventions should be discussed with an experienced medical professional.
The impact of lifestyle on cancer risk should be discussed e.g. exercise most days for at least 30 minutes at moderate or strenuous intensity, maintain a healthy weight, have a healthy diet, limit alcohol intake, do not smoke and avoid excessive sun exposure.
Cancer/tumour type |
Recommendationsr |
|
|
Age |
Strategy and frequency |
Renal cell carcinoma |
Surveillance |
From age 10 years |
Abdominal MRI 2nd yearly with abdominal ultrasound in intervening years |
Pancreatic neuroendocrine tumours |
Surveillance |
From age 10 years |
Abdominal MRI 2nd yearly with abdominal ultrasound in intervening years |
Phaeochromocytoma |
Surveillance |
From age 2 years |
- Annual physical examination with BP
- Annual fasting free plasma metanephrines and if available plasma 3-methoxytyramine (if plasma unavailable 24-hour urine free metanephrines)
|
Genotype-phenotype correlations (VHL type1, type2A-C) are not yet well enough defined to justify distinct surveillance paradigms.
The utility of nuclear scans for routine screening in the detection of von Hippel-Lindau disease-associated tumours remains unclear.
See also Measurement and tests for biogenic amines including information for patients who are having tests