To see all protocols that comply with the WHO Essential Medicine List 

The following is a list of some drugs that may be associated with QTc interval prolongation. This list is not exhaustive.

Class Drugs (in therapeutic doses)
Antiarrhythmics amiodarone, disopyramide, dofetilide*, procainamide, quinidine, sotalol
Antipsychotics amisulpride, chlorpromazine, clozapine, droperidol, fluphenazine, haloperidol, pimozide*, risperidone, sertindole*, thioridiazine*, ziprasidone
Antidepressants citalopram, escitalopram, fluoxetine, lithium, moclobemide, tricyclic antidepressants (e.g. amitriptyline, clomipramine, dosulepin (doxepin), dothiepin, imipramine)
Antibiotics azithromycin, clarithromycin, erythromycin, metronidazole (with alcohol), moxifloxacin, pentamidine, roxithromycin, sparfloxacin*
Antifungals fluconazole, ketoconazole, voriconazole
Antivirals atazanavir, lopinavir, nelfinavir
Antimalarials chloroquine, mefloquine, quinine
Antineoplastics anagrelide, arsenic trioxide, cabozantinib, ceritinib, crizotinib, dabrafenib, dasatinib, degarelix, eribulin, goserelin, lapatinib, lenvatinib, leuprorelin, nilotinib, osimertinib, oxaliplatin, pazopanib, ribociclib, romidepsin, sorafenib, sunitinib, toremifene, triptorelin, vandetanib, vemurafenib
Miscellaneous 5HT3 antagonists (e.g. dolasetron, ondansetron), astemizole*, cisapride, cocaine, dextropropoxyphene, domperidone, fingolimod*, methadone, pasireotide, probucol*, solifenacin, tacrolimus, terfenadine*, tetrabenazine, vardenafil

* not readily available in Australia

While every effort has been made to ensure the accuracy of the content at the time of publication, the Cancer Institute NSW does not accept any liability, with respect to loss, damage, injury or expense arising from any such errors or omission in the contents of this work. Any reference to specific pharmaceuticals and/or medical products as examples does not imply endorsement of any of these products. Use is subject to eviQ’s disclaimer available at

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29 Feb 2020