To see all protocols that comply with the WHO Essential Medicine List 

This fact sheet contains general information about Cowden syndrome. Each person should see a genetic service for further information and advice. 

Key Points

  • Cowden syndrome/PTEN Hamartoma syndrome is caused by faults (mutations) in the PTEN gene.
  • Both men and women with PTEN Hamartoma syndrome have an increased chance of developing thyroid cancer and kidney cancer.
  • Women with PTEN Hamartoma syndrome have an increased chance of developing breast and uterine (endometrial) cancer.
  • Both men and women with PTEN Hamartoma syndrome have an increased chance of developing bowel polyps.
  • Men and women can be referred to a genetic service where experts can provide information, support and advice about their chance of developing cancer and the option of genetic testing.

This cancer genetics fact sheet is a guide only and cannot cover every possible situation. The information provided is not intended to replace discussion with a health professional, and should not be interpreted as medical advice. Use of this document is subject to eviQ's disclaimer available at  www.eviQ.org.au  

Send feedback for this page


First approved:
Last reviewed:
Review due:

The currency of this information is guaranteed only up until the date of printing, for any updates please check:

https://www.eviq.org.au/p/3436

17 Nov 2019