Pregnancy
While studies are conflicting, there may be a risk of progression of cerebellar haemangioblastomas during pregnancy. Undiagnosed phaeochromocytoma may pose additional risks during pregnancy, especially during labour and delivery. Consider referral to a specialist high-risk pregnancy unit.
Hearing loss and vestibulopathy
Irreversible hearing loss, tinnitus, vertigo and cranial nerve dysfunction can occur due to endolymphatic sac tumours. The early detection of hearing loss and vestibulopathy and surgical intervention can preserve hearing and ameliorate vestibular symptoms.r
Renal cell carcinoma
Multicentric and bilateral RCCs are common. Where possible, the management of renal cell carcinomas should be undertaken in a unit with expertise in nephron-sparing surgery.