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This fact sheet contains general information. Each person should be referred to a genetic service for further information and advice about what a faulty CDKN2A gene means for them.

Key Points

  • People with a faulty CDKN2A gene have an increased chance of developing melanoma.
  • People with a specific fault in the CDKN2A gene have an increased chance of developing pancreatic cancer. 
  • People who have a relative with a faulty CDKN2A gene, but do not have it themselves, may still have an increased chance of developing melanoma. This chance is smaller than the chance for relatives with the faulty gene. 
  • Family members can be referred to a genetic service where experts can provide information, advice and support about their chance of developing cancer and the option of genetic testing.  

This cancer genetics fact sheet is a guide only and cannot cover every possible situation. The information provided is not intended to replace discussion with a health professional, and should not be interpreted as medical advice. While eviQ endeavours to link to reliable sources that provide accurate information, eviQ and the Cancer Institute NSW do not endorse or accept responsibility for the accuracy, currency, reliability or correctness of the content of linked external information sources. Use of this document is subject to eviQ's disclaimer available at  

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04 Mar 2024