This fact sheet contains general information. Each person should be referred to a genetic service for further information and advice about what a faulty SDHD gene means for them. 

Key Points

  • People with a faulty SDHD gene who have inherited it from their father have an increased chance of developing paraganglioma and phaeochromocytoma. They also have a small increased chance of developing kidney (renal) cancer and a tumour in the stomach/intestine called a gastrointestinal stromal tumour (GIST).
  • People with a faulty ​SDHD gene who have inherited it from their mother do not have a significantly increased chance of developing paraganglioma, phaeochromocytoma, kidney cancer or GIST. However, they may still pass the faulty gene onto their children.
  • Family members (including children) can be referred to a genetic service where experts can provide information, advice and support about their risk of cancer and the option of genetic testing.

This cancer genetics fact sheet is a guide only and cannot cover every possible situation. The information provided is not intended to replace discussion with a health professional, and should not be interpreted as medical advice. While eviQ endeavours to link to reliable sources that provide accurate information, eviQ and the Cancer Institute NSW do not endorse or accept responsibility for the accuracy, currency, reliability or correctness of the content of linked external information sources. Use of this document is subject to eviQ's disclaimer available at www.eviQ.org.au/copyright  

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https://www.eviq.org.au/p/3618

13 Apr 2024