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This fact sheet contains general information about HPT-JT syndrome. Each person should be referred to a genetic service for further information and advice. 

Key Points

  • HPT-JT syndrome is due to faults (mutations) in the CDC73 gene.
  • People with HPT-JT syndrome have an increased chance of developing parathyroid disease including parathyroid cancer.
  • People with HPT-JT syndrome have an increased chance of developing benign (non-cancerous) tumours of the jaw (ossifying fibromas) and tumours and cysts of the kidney.
  • Women with HPT-JT syndrome have an increased chance of developing benign tumours of the uterus (uterine fibroids).
  • Family members (including children) can be referred to a genetic service where experts can provide information, advice and support about their chance of developing cancer and the option of genetic testing.

This cancer genetics fact sheet is a guide only and cannot cover every possible situation. The information provided is not intended to replace discussion with a health professional, and should not be interpreted as medical advice. While eviQ endeavours to link to reliable sources that provide accurate information, eviQ and the Cancer Institute NSW do not endorse or accept responsibility for the accuracy, currency, reliability or correctness of the content of linked external information sources. Use of this document is subject to eviQ's disclaimer available at  www.eviQ.org.au  

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https://www.eviq.org.au/p/3640

26 Nov 2022