BAP1 is a ‘tumour protection’ gene that helps to protect against benign skin tumours, melanoma, mesothelioma and kidney cancer.
Everyone has two BAP1 genes (one from their mother, and one from their father). If one of the genes is not working, this is known as having a faulty BAP1 gene, or having a BAP1 mutation. People with a faulty BAP1 gene are known to have BAP1-tumour predisposition syndrome (BAP1-TPDS).