There is insufficient data demonstrating improved outcome to recommend routine screening of individuals at high risk. However there is accumulating evidence that screening may detect pre-invasive lesions which may allow for early intervention. Canto et al. in collaboration with The cancer of the pancreas screening consortium (CAPS) favours endoscopic US or MRI/MR cholangiopancreatography as the most accurate tool for pancreatic imaging, particularly as it does not involve ionising radiation and allows for the collection of samples to identify precursor lesions.r
Two recently reported surveillance studies have shown that the majority of significant lesions have been found in older patients.r Canto et al. report the prevalence of pancreatic lesions in high risk individuals was age related with a significant difference found in the number of lesions detected between patients <50 years old compared to >50 years old. All pancreatic lesions with high grade dysplasia were in patients >65 years old. Ludwig et al. similarly report a significant abnormality was found in 35% high risk individuals >65 years of age compared to 3% in those <65 years of age.