To see all protocols that comply with the WHO Essential Medicine List 

Grade 1: mild; asymptomatic or mild symptoms; clinical or diagnostic observations only; intervention not indicated

Grade 2: moderate; minimal, local or noninvasive intervention indicated; limiting age-appropriate instrumental activities of daily living

Grade 3: severe or medically significant but not immediately life threatening; hospitalisation or prolongation of hospitalisation indicated; disabling; limiting self care activities of daily living

Grade 4: life threatening consequences; urgent intervention indicated

Adapted from Common Terminology Criteria for Adverse Events (CTCAE) Version 5.0 Published: November 27, 2017