It is the consensus opinion of the medical oncology reference committee that this protocol is not considered best practice for this patient population as weekly paclitaxel is preferable in most circumstances.
Treatment Schedule Summary
Drug |
Dose |
Route |
Day |
PACLItaxel |
175 mg/m2 |
IV |
1 |
Trastuzumab |
4 mg/kg (loading dose only); 2 mg/kg (subsequent doses) |
IV |
1, 8, 15 |
Frequency: 21 days
Cycles: Continuous until disease progression or unacceptable toxicity (weekly trastuzumab to be continued after completion of paclitaxel chemotherapy)