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This protocol is based on limited evidence; please refer to the evidence section of this protocol for more information.

This protocol replaces a previous version ID 1671 Glioblastoma recurrent single agent lomustine with lomustine starting dose 130 mg/m2 which has been discontinued. It is the consensus of the eviQ reference committee to use a starting dose of 110 mg/m2 in this patient population based on the dose of lomustine used in recent clinical trialsrrr and due to toxicity concerns in these heavily pre-treated patients.

The information contained in this protocol is based on the highest level of available evidence and consensus of the eviQ reference committee regarding their views of currently accepted approaches to treatment. Any clinician (medical oncologist, haematologist, radiation oncologist, medical physicist, radiation therapist, pharmacist or nurse) seeking to apply or consult this protocol is expected to use independent clinical judgement in the context of individual clinical circumstances to determine any patient's care or treatment. Use is subject to eviQ’s disclaimer available at www.eviQ.org.au

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The currency of this information is guaranteed only up until the date of printing, for any updates please check:

https://www.eviq.org.au/p/3363

15 Dec 2018