To see all protocols that comply with the WHO Essential Medicine List 
 ID 3521 - technical system issue:

Due to a technical system issue a bolus dose of fluorouracil i.e. ‘fluorouracil 400 mg/m2 IV over 3-5 minutes’  was displayed in the treatment schedule (overview and detail) of this protocol between 18 December 2022 to 9 January 2023. The protocol was amended and re-published on 9 January 2023. For further information please contact

 Fluoropyrimidine overdose or overexposure:

Fluoropyrimidine overdose or overexposure may result in severe or life-threatening toxicity. An antidote is available and is highly effective if given within 96 hours.  Read more about fluoropyrimidine overdose or overexposure.

Check for clinical trials in this patient group. Link to Australian Clinical Trials website

The anticancer drug(s) in this protocol have been updated with the ADDIKD guideline recommendations (if applicable). Recommendations may differ from other protocols which have not been updated. For further information refer to the dedicated eviQ ADDIKD guideline webpage.

There are multiple FOLFIRINOX (modified) protocols. This is the adjuvant pancreatic cancer protocol. 

The information contained in this protocol is based on the highest level of available evidence and consensus of the eviQ reference committee regarding their views of currently accepted approaches to treatment. Any clinician (medical oncologist, haematologist, radiation oncologist, medical physicist, radiation therapist, pharmacist or nurse) seeking to apply or consult this protocol is expected to use independent clinical judgement in the context of individual clinical circumstances to determine any patient's care or treatment. While eviQ endeavours to link to reliable sources that provide accurate information, eviQ and the Cancer Institute NSW do not endorse or accept responsibility for the accuracy, currency, reliability or correctness of the content of linked external information sources. Use is subject to eviQ’s disclaimer available at

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01 Mar 2024