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Breast invasive cancer adjuvant EBRT hypofractionation whole breast DISCONTINUED

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This protocol has been discontinued as an alternative protocol is available ID 3650 Breast invasive cancer adjuvant whole breast EBRT

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Version 6

Date Summary of changes
15/12/2008 Approved on CI-SCaT.
24/08/2009 Reviewed and transferred to eviQ.
29/11/2010 Lung OAR doses clarified as combined lung doses.
1/07/2011 Heart OAR dose added based on QUANTEC data by Gagliardi et al 2010 - V25Gy < 10% for a 1% probability of cardiac mortality 15 years post RT.
2/09/2013
Protocol reviewed at reference committee meeting 22 Sept 2011. Following changes were made:
  • Nodal information removed and added to a seperate nodal irradiation protocol. See ID:1282
  • Target volume contouring example linked to RTOG Breast contouring atlas
  • Organs at Risk (OARs) standardised across all breast protocols
  • Efficacy based on NSABP-B06 trial (Fisher 2002) and EBCTCG Meta-analysis (Clarke 2005)
  • Side effects updated
  • Review Group - 2
10/04/2014 Heart OAR point amended to read :
  • <10% of the heart should receive 50% of prescribed dose for a 1% probability of cardiac mortality 15 years post RT(Gagliardi et al, 2010 IJROBP 76:S77-85).
01/04/2016 Protocol reviewed at December 2015 RCM and Approved to be published.
31/05/2017 Transferred to new eviQ website.
13/09/2019

Reviewed at Reference Committee Meeting 13th June 2019. Consensus to combine protocol with ID 1922 Breast invasive cancer adjuvant EBRT conventional whole breast.

Protocols combined under new protocol ID 3650. ID 1922 and 1923 discontinued.

The information contained in this protocol is based on the highest level of available evidence and consensus of the eviQ reference committee regarding their views of currently accepted approaches to treatment. Any clinician (medical oncologist, haematologist, radiation oncologist, medical physicist, radiation therapist, pharmacist or nurse) seeking to apply or consult this protocol is expected to use independent clinical judgement in the context of individual clinical circumstances to determine any patient's care or treatment. Use is subject to eviQ’s disclaimer available at www.eviQ.org.au

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First approved:
Last reviewed:
Discontinued:

The currency of this information is guaranteed only up until the date of printing, for any updates please check:

https://www.eviq.org.au/p/1923

21 Sep 2019