Investigations and diagnosis
- steroid induced diabetes
- pneumocystis jiroveci (formerly carinii) pneumonia
- proximal myopathy
- skin fragility
- steroid induced psychosis
- gastric and duodenal ulcers and perforation.
Dexamethasone may also increase the metabolism of anticonvulsant medications, leading to sub-therapeutic levels or toxicity when the dose of steroid is lowered.
For patients requiring high doses (greater than 4 mg) of dexamethasone, for protracted periods, check blood sugar levels (BSL) and monitor anticonvulsants (be aware that the dexamethasone may suppress the allergic rash from phenytoin or carbamazepine and it may only appear as the steroid dose is lowered).