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This fact sheet contains general information about Hereditary Leiomyomatosis and Renal Cell Carcinoma (HLRCC). Each person should be referred to a genetic service for further information and advice.

Key Points

  • HLRCC is caused by faults (mutations) in the FH gene.
  • People with HLRCC have an increased chance of developing kidney (renal) cancer and  benign (non-cancerous) skin lesions (leiomyoma).
  • Women with HLRCC have an increased chance of developing uterine fibroids (leiomyoma).
  • Family members (including teenagers) can be referred to a genetic service where experts can provide information, advice and support about their chance of developing cancer and the option of genetic testing.   

This cancer genetics fact sheet is a guide only and cannot cover every possible situation. The information provided is not intended to replace discussion with a health professional, and should not be interpreted as medical advice. While eviQ endeavours to link to reliable sources that provide accurate information, eviQ and the Cancer Institute NSW do not endorse or accept responsibility for the accuracy, currency, reliability or correctness of the content of linked external information sources. Use of this document is subject to eviQ's disclaimer available at  www.eviQ.org.au  

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https://www.eviq.org.au/p/3437

15 Jun 2021