To see all protocols that comply with the WHO Essential Medicine List 

Grade 1: macules/papules covering < 10% BSA with or without symptoms (e.g. pruritis, burning, tightness)

Grade 2: macules/papules covering 10 - 30% BSA with or without symptoms (e.g., pruritus, burning, tightness); limiting instrumental activities of daily living; rash covering > 30% BSA with or without mild symptoms

Grade 3: macules/papules covering >30% BSA with moderate or severe symptoms; limiting self care activities of daily living

Reference: Common Terminology Criteria for Adverse Events (CTCAE) Version 5.0 Published: November 27, 2017